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FHIR Interoperability Resource Center

The latest guides, tools and insights on healthcare interoperability, FHIR standards, and secure, compliant data exchange for innovative healthcare organizations.

eBook
  • The Payer-to-Payer Gap: From CMS-0057 Compliance to Real Data Exchange
  • A playbook on why a compliant Payer-to-Payer API isn't the same as real data exchange, with a case study on closing that gap.
eBook
  • Why Standing Up Technically Compliant CMS-0057 APIs Is Not Enough
  • An ebook on how network strategy, provider relationships, and member workflows power healthcare data exchange.
eBook
  • CMS-0057 Audit Readiness Quick-Start Guide
  • A quick-start guide to building defensible API audit logs ahead of CMS-0057 enforcement.
Demo
  • 1up Electronic Prior Authorization Demo
  • A hands-on walkthrough of the provider portal, EHR submission workflow, and the 1up Console reporting dashboard.

Videos

Understanding FHIR
Video
  • Understanding FHIR
  • A plain-language introduction to what FHIR is and why it matters for health data exchange.
How FHIR Works
Video
  • How FHIR Works
  • A closer look at how FHIR standards actually move and structure health data.

Briefs, eBooks, Reports & more

Stay up to date with the latest from 1upHealth​

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Payer to Payer Data Exchange
Product Sheet
  • 1up Payer-to-Payer Data Exchange
  • Unlock historical member data to improve onboarding and close care gaps.
illustration of the electronic prior authorization process
Product Sheet
  • 1up Electronic Prior Authorization
  • Automate prior authorization to deliver faster decisions and better experiences.
Product Sheet
  • 1up Provider Access
  • Enable providers with timely patient data for better care decisions.
Product Sheet
  • 1up Provider Directory Product Sheet
  • Publish accurate provider directories that make in-network care easy to find.
1upHealth 2025 Payer’s Guide to Interoperability ebook
eBookHow-to Guide
  • Payer’s Guide to Interoperability: How to plan, implement, and maximize value for CMS-0057
  • An ebook covering what CMS-0057 requires, checklists for getting your health plan ready, and the technical foundation you'll need.
1upHealth: FHIR & the Art of the Possible Web Series Episode 1
Video
  • FHIR & the Art of the Possible
  • A web series exploring what's possible in healthcare once FHIR-based interoperability is in place.
1up Patient Access
Product Sheet
  • 1up Patient Access
  • Learn how to give members easy, secure access to their health information.
1upHealth Spotlight
  • Glossary
  • Plain-language definitions of the FHIR, interoperability, and CMS terms you'll run into most often.
Questions and Answers
  • CMS Final Rule FAQs
  • Quick answers to the most common questions about what CMS-0057-F and CMS-9115-F actually require.
Pharmacist using a tablet
Regulatory Brief
  • Provider Directory API
  • A breakdown of the CMS Provider Directory requirement and what it takes to keep listings accurate and compliant.
1up Provider Access API visualized with doctor on a tablet
Regulatory Brief
  • Provider Access API
  • A breakdown of the CMS Provider Access API requirement and how to share data with in-network providers.
1up Population Connect​ product visualized with a doctor and patient looking at the data from a wearable health technology device
Regulatory Brief
  • Patient Access API
  • A breakdown of the CMS Patient Access API requirement and what health plans need to support it.
1up Payer-to-Payer Data Exchange API visualized with man sitting in office in front of a large computer screen
Regulatory Brief
  • Payer-to-Payer API
  • A breakdown of the CMS Payer-to-Payer requirement and how FHIR APIs support it.
Prior Authorization visualized with a healthcare worker on a laptop with a document on the screen showing a signature and checkmark
Regulatory Brief
  • Prior Authorization API
  • A breakdown of the CMS Prior Authorization API requirement and its impact on turnaround times.
Inside the Beltway Featuring Dr. Don Rucker
Video
  • Inside the Beltway: A Conversation with Dr. Don Rucker
  • A series featuring former National Coordinator for Health IT Dr. Don Rucker on the state of health data policy.

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