Are you ready for CMS-0057 and future interoperability requirements?

1upHealth is the interoperability vendor of choice for 80+ Medicare, Medicaid, and commercial payers. Learn why.

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What’s Your Interoperability Strategy?

According to WEDI’s 2025 “CMS Interoperability and Prior Authorization Final Rule Survey”, the majority of payer respondents had not yet started preparing for compliance with CMS-0057 API requirements. With the deadline looming, now is the time to act.

Your approach to Patient Access and Interoperability (CMS-9115) compliance will not suffice for Prior Authorization and Interoperability (CMS-0057), which is much more complex and far-reaching.

Now is the perfect time to rethink your interoperability strategy and the technology foundation required.

Health Data, On Demand

1upHealth is the market leader helping Medicare, Medicaid, and commercial payers easily acquire, manage, share, and analyze health data in real time and at scale, supporting not only their regulatory requirements but also helping them drive ROI from their interoperability investments.

Make the Move to 1upHealth​

Go from Basic Data Exchange to Computable Interoperability

Go beyond the batch and highly manual movement of data and turn health data into a continuous stream of actionable information that can be combined, analyzed, and used across systems in near real time.

Go from Compliance to Interoperability as a Strategic Advantage

Go beyond satisfying regulatory requirements to make interoperability a strategic advantage for improvements in areas like Star Ratings, quality management, risk adjustment, care management, and member and provider engagement.

Go from Dated Architecture to the Leading Health Data Management Platform (HDMP)​

The 1up Platform is the market's most advanced, FHIR-native HDMP. Purpose-built for healthcare on a next-generation data lakehouse architecture, our platform leverages industry-standard, open-source technologies for real-time exchange and analytics.

What our customers are saying

Why Payers Have Made the Move to 1upHealth

Building the future of healthcare is no small task. We believe that to solve tough problems, we need to be guided by our Core Values:

Industry Leader

An industry-leading, standards-first, FHIR-native platform.

Robust Compliance

A dedication to compliance, with the most CMS FHIR APIs in the industry.

Industry Experts

Deep industry experience, with a customer base of 80+ payers.

Hands On

Dedicated account teams driving meaningful outcomes.

Speed & Support

Fast implementations and 24/7/365 US-based support​.

Flexibility

Ready to support you at every stage of your interoperability journey.

Endpoint Network

A powerful network of 7,500+ provider and 130+ payer endpoints.

Competitive Pricing

Competitive pricing to earn your business​.

Additional Resources

Ready to Learn More About Healthcare’s Modern Data Platform?

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